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As a next-generation triple receptor agonist, Retatrutide simultaneously targets GLP-1, GIP, and glucagon receptors, making it a valuable compound for metabolic, endocrine, and energy-regulation research

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Tolerability and Safety Questions Both candidates are likely to be judged partly on gastrointestinal tolerability: nausea, vomiting, diarrhea, constipation, dose escalation, and discontinuation due to adverse events

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No prospective randomized trials are available on this matter